Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio

BACKGROUND: Osteopontin (OPN) is an immunoregulatory protein which production increases in both rheumatoid arthritis (RA) and osteoarthritis (OA). Phosphorylated osteopontin (Phospho-OPN) is known to increase macrophage and osteoclast activation, this process is controlled by extracellular tartrate-...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Luukkonen, Jani, Pascual, Laia Mira, Patlaka, Christina, Lång, Pernilla, Turunen, Sanna, Halleen, Jussi, Nousiainen, Tomi, Valkealahti, Maarit, Tuukkanen, Juha, Andersson, Göran, Lehenkari, Petri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549736/
https://ncbi.nlm.nih.gov/pubmed/28792533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182904
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