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Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation

Calcium functions as a trigger for the switch between epithelial cell growth and differentiation. We report here that the calcium/calmodulin-dependent phosphatase calcineurin is involved in this process. Treatment of primary mouse keratinocytes with cyclosporin A, an inhibitor of calcineurin activit...

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Detalhes bibliográficos
Main Authors: Santini, Maria Paola, Talora, Claudio, Seki, Toshihiko, Bolgan, Loretta, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55494/
https://ncbi.nlm.nih.gov/pubmed/11493684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161299698
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