Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation

Calcium functions as a trigger for the switch between epithelial cell growth and differentiation. We report here that the calcium/calmodulin-dependent phosphatase calcineurin is involved in this process. Treatment of primary mouse keratinocytes with cyclosporin A, an inhibitor of calcineurin activit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Santini, Maria Paola, Talora, Claudio, Seki, Toshihiko, Bolgan, Loretta, Dotto, G. Paolo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11493684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.161299698
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