Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

BACKGROUND: Sequence-specific PCR is the most common approach for virus identification in diagnostic laboratories. However, as specific PCR only detects pre-defined targets, novel virus strains or viruses not included in routine test panels will be missed. Recently, advances in high-throughput seque...

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Detalhes bibliográficos
Publicado no:Microbiome
Main Authors: Lewandowska, Dagmara W., Zagordi, Osvaldo, Geissberger, Fabienne-Desirée, Kufner, Verena, Schmutz, Stefan, Böni, Jürg, Metzner, Karin J., Trkola, Alexandra, Huber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549297/
https://ncbi.nlm.nih.gov/pubmed/28789678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0317-z
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