Serum Antibodies against Helicobacter pylori Neutrophil Activating Protein in Carriers of IL-4 C-590T Genetic Polymorphism Amplify the Risk of Gastritis and Gastric Cancer

BACKGROUND: Gastric cancer arises, mainly, on an inflammatory background. Helicobacter pylori neutrophil activating (HP-NAP) protein functions as a potent pro-inflammatory mediator. Similarly, IL-4 plays a critical role in the inflammation pathway, the levels of which are altered by C to T transitio...

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Pubblicato in:Iran Biomed J
Autori principali: Talebkhan, Yeganeh, Doozbakhshan, Mohsen, Saberi, Samaneh, Esmaeili, Maryam, Karami, Najmeh, Mohajerani, Nazanin, Abdirad, Afshin, Hosseini, Mahmoud Eshagh, Nahvijou, Azin, Mohagheghi, Mohammad Ali, Mohammadi, Marjan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Pasteur Institute 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548964/
https://ncbi.nlm.nih.gov/pubmed/27677314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18869/acadpub.ibj.21.5.321
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