Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness

The quantitative sensitivity and dynamic range of conventional immunohistochemistry (IHC) with 3,3′-diaminobenzidine (IHC-DAB) used in pathological diagnosis in hospitals are poor, because enzyme activity can affect the IHC-DAB chromogenic reaction. Although fluorescent IHC can effectively increase...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gonda, Kohsuke, Watanabe, Mika, Tada, Hiroshi, Miyashita, Minoru, Takahashi-Aoyama, Yayoi, Kamei, Takashi, Ishida, Takanori, Usami, Shin, Hirakawa, Hisashi, Kakugawa, Yoichiro, Hamanaka, Yohei, Yoshida, Ryuichi, Furuta, Akihiko, Okada, Hisatake, Goda, Hideki, Negishi, Hiroshi, Takanashi, Kensaku, Takahashi, Masaru, Ozaki, Yuichi, Yoshihara, Yuka, Nakano, Yasushi, Ohuchi, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548777/
https://ncbi.nlm.nih.gov/pubmed/28790306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06534-z
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