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Mesenchymal cell-specific MyD88 signaling promotes systemic dissemination of Salmonella Typhimurium via inflammatory monocytes

Enteric pathogens including Salmonella enteric serovar Typhimurium can breach the epithelial barrier of the host and spread to systemic tissues. In response to infection, the host activates innate immune receptors via the signaling molecule MyD88 that induces protective inflammatory and anti-microbi...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Kim, Donghyun, Seo, Sang-Uk, Zeng, Melody Y., Kim, Wan-Uk, Kamada, Nobuhiko, Inohara, Naohiro, Núñez, Gabriel
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548622/
https://ncbi.nlm.nih.gov/pubmed/28674182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601527
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