Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy

Expansion microscopy (ExM), a method for improving the resolution of light microscopy by physically expanding the specimen, has not been applied to clinical tissue samples. Here we report a clinically optimized form of ExM that supports nanoscale imaging of human tissue specimens that have been fixe...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Zhao, Yongxin, Bucur, Octavian, Irshad, Humayun, Chen, Fei, Weins, Astrid, Stancu, Andreea L., Oh, Eun-Young, DiStasio, Marcello, Torous, Vanda, Glass, Benjamin, Stillman, Isaac E., Schnitt, Stuart J., Beck, Andrew H., Boyden, Edward S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548617/
https://ncbi.nlm.nih.gov/pubmed/28714966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3892
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