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Psychosine, a marker of Krabbe phenotype and treatment effect

Newborn screening (NBS) for Krabbe disease, a rare neurodegenerative disorder caused by deficient galactocerebrosidase (GALC) enzyme activity, has recently been implemented in a number of US states. However, the spectrum of phenotypic manifestations associated with deficient GALC activity complicate...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Escolar, ML, Kiely, BT, Shawgo, E, Hong, X, Gelb, MH, Orsini, JJ, Matern, D, Poe, MD
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548593/
https://ncbi.nlm.nih.gov/pubmed/28579020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2017.05.015
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