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Genetic Screening of Selected Disease-Causing Mutations in Glutaryl-CoA Dehydrogenase Gene among Indian Patients with Glutaric Aciduria Type I

Glutaric aciduria type I (GA-I) is an organic aciduria caused by glutaryl-CoA dehydrogenase (GCDH) deficiency. There are limited studies on GA-I from India. A total of 48 Indian GA-I patients were screened for selected disease-causing mutations such as R402W, A421V, A293T, R227P, and V400M using pol...

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Publié dans:J Pediatr Genet
Auteurs principaux: TP, Kruthika-Vinod, Muntaj, Shaik, Devaraju, K. S., Kamate, M., Vedamurthy, A. B.
Format: Artigo
Langue:Inglês
Publié: Georg Thieme Verlag KG 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548524/
https://ncbi.nlm.nih.gov/pubmed/28794906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1599202
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