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Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders

Matrix metalloproteinases (MMPs) are zinc-dependent proteolytic enzymes that degrade various proteins in the extracellular matrix (ECM). MMPs may also regulate the activity of membrane receptors and post-receptor signaling mechanisms, and thereby affect cell function. The MMP family includes collage...

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Pubblicato in:Prog Mol Biol Transl Sci
Autori principali: Liu, Jie, Khalil, Raouf A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548434/
https://ncbi.nlm.nih.gov/pubmed/28662828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2017.04.003
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