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X-rays and metformin cause increased urinary excretion of cell-free nuclear and mitochondrial DNA in aged rats

Activation of cell death in mammals can be assessed by an increase of an amount of cell-free DNA (cf-DNA) in urine or plasma. We investigated the excretion of cf nuclear DNA (nDNA) and cf mitochondrial DNA (mtDNA) in the urine of rats 3 and 24 months in age after X-irradiation and metformin administ...

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Detalhes bibliográficos
Publicado no:J Circ Biomark
Main Authors: Gaziev, Azhub, Abdullaev, Serazhutdin, Minkabirova, Gulchachak, Kamenskikh, Kristina
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548319/
https://ncbi.nlm.nih.gov/pubmed/28936265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1849454416670782
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