Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies

Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which forms at reduced temperatures, may affect EV isolation and may...

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Vydáno v:J Circ Biomark
Hlavní autoři: Wachalska, Magda, Koppers-Lalic, Danijela, van Eijndhoven, Monique, Pegtel, Michiel, Geldof, Albert A., Lipinska, Andrea D., van Moorselaar, R. Jeroen, Bijnsdorp, Irene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548314/
https://ncbi.nlm.nih.gov/pubmed/28936252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5772/62579
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