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Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

Live Mycobacterium tuberculosis persists in macrophage phagosomes by interfering with phagolysosome biogenesis. Here, using four-dimensional microscopy and in vitro assays, we report the principal difference between phagosomes containing live and dead mycobacteria. Phosphatidylinositol 3-phosphate (...

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Detalhes bibliográficos
Main Authors: Vergne, Isabelle, Chua, Jennifer, Lee, Hwang-Ho, Lucas, Megan, Belisle, John, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554822/
https://ncbi.nlm.nih.gov/pubmed/15753315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409716102
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