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B Cell Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B cell Immune Responses
MyD88 and FcR common gamma chain (Fcer1g, FcRγ) elicit proinflammatory responses to exogenous antigens. Deletion of these receptors in autoimmune models has generally led to reduced overall disease. In B cells, Myd88 is required for anti-DNA and anti-RNA autoAb responses, while Fcer1g is not express...
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| Опубликовано в: : | J Immunol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547912/ https://ncbi.nlm.nih.gov/pubmed/28659358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600861 |
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