Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

BACKGROUND: p53 mutations are relatively uncommon in medulloblastoma, but abnormalities in this cell cycle pathway have been associated with anaplasia and worse clinical outcomes. We correlated p53 protein expression with pathological subtype and clinical outcome in 75 embryonal brain tumors. The pr...

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Hlavní autoři: Eberhart, Charles G, Chaudhry, Aneeka, Daniel, Richard W, Khaki, Leila, Shah, Keerti V, Gravitt, Patti E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC554768/
https://ncbi.nlm.nih.gov/pubmed/15717928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-19
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