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Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid–Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder

IMPORTANCE: Dysfunction related to γ-aminobutyric acid (GABA)–ergic neurotransmission in the pathophysiology of major psychosis has been well established by the work of multiple groups across several decades, including the widely replicated downregulation of GAD1. Prior gene expression and network a...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Ruzicka, W. Brad, Subburaju, Sivan, Benes, Francine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547581/
https://ncbi.nlm.nih.gov/pubmed/25738424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2015.49
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