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Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid–Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder

IMPORTANCE: Dysfunction related to γ-aminobutyric acid (GABA)–ergic neurotransmission in the pathophysiology of major psychosis has been well established by the work of multiple groups across several decades, including the widely replicated downregulation of GAD1. Prior gene expression and network a...

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Pubblicato in:JAMA Psychiatry
Autori principali: Ruzicka, W. Brad, Subburaju, Sivan, Benes, Francine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547581/
https://ncbi.nlm.nih.gov/pubmed/25738424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2015.49
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