SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

BACKGROUND: Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs demonstrated that secreted frizzled-related protein 2 (SFRP2), a Wnt inhibitor,...

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Udgivet i:Cell Mol Biol Lett
Main Authors: Jin, Luyuan, Cao, Yu, Yu, Guoxia, Wang, Jinsong, Lin, Xiao, Ge, Lihua, Du, Juan, Wang, Liping, Diao, Shu, Lian, Xiaomeng, Wang, Songlin, Dong, Rui, Shan, Zhaochen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547503/
https://ncbi.nlm.nih.gov/pubmed/28794794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-017-0044-2
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