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Redox Paradox: Can Hypoxia Heal Ischemic Hearts?

Adult cardiomyocytes are largely thought to lack proliferative and therefore regenerative potential. Reporting in Nature, Nakada et al. (2016) find that a hypoxic regime reduces mitochondrial metabolism and promotes proliferation in adult mouse cardiomyocytes, resulting in increased regeneration fol...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Guimarães-Camboa, Nuno, Evans, Sylvia M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547440/
https://ncbi.nlm.nih.gov/pubmed/27875683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.11.007
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