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All six GC-motifs of the SV40 early upstream element contribute to promoter activity in vivo and in vitro.

Recombinants in which the six GC-motifs (I-VI) present in the upstream element of the SV40 early promoter region have been point mutated either individually or in pairs were used to determine the possible contribution of each GC-motif to the function of the overlapping early-early and late-early SV4...

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Autori principali: Barrera-Saldana, H, Takahashi, K, Vigneron, M, Wildeman, A, Davidson, I, Chambon, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC554739/
https://ncbi.nlm.nih.gov/pubmed/3004974
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