CHOP Deficiency Ameliorates ERK5 Inhibition-Mediated Exacerbation of Streptozotocin-Induced Hyperglycemia and Pancreatic β-Cell Apoptosis

Streptozotocin (STZ)-induced murine models of type 1 diabetes have been used to examine ER stress during pancreatic β-cell apoptosis, as this ER stress plays important roles in the pathogenesis and development of the disease. However, the mechanisms linking type 1 diabetes to the ER stress-modulatin...

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Vydáno v:Mol Cells
Hlavní autoři: Nam, Dae-Hwan, Han, Jung-Hwa, Lim, Jae Hyang, Park, Kwon Moo, Woo, Chang-Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Molecular and Cellular Biology 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547215/
https://ncbi.nlm.nih.gov/pubmed/28681594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.2296
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