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Anti-Z-DNA antibody binding can stabilize Z-DNA in relaxed and linear plasmids under physiological conditions.

It is shown that anti-Z-DNA antibody binding can stabilize sequences of d(CG/GC)n and d(CA/GT)n in the Z-DNA conformation in a plasmid in the complete absence of supercoiling. This effect is quantitated by using antibody preparations of different affinities and varying concentrations. The d(CG/GC)n...

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Udgivet i:EMBO J
Principais autores: Lafer, E M, Sousa, R, Rich, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4092691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb04131.x
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