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A Combined PLS and Negative Binomial Regression Model for Inferring Association Networks from Next-generation Sequencing Count Data

A major challenge of genomics data is to detect interactions displaying functional associations from large-scale observations. In this study, a new cPLS-algorithm combining partial least squares approach with negative binomial regression is suggested to reconstruct a genomic association network for...

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Detalhes bibliográficos
Publicado no:IEEE/ACM Trans Comput Biol Bioinform
Main Authors: Pesonen, Maiju, Nevalainen, Jaakko, Potter, Steven, Datta, Somnath, Datta, Susmita
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547023/
https://ncbi.nlm.nih.gov/pubmed/28186904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2017.2665495
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