Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s)

Inhalation delivery of prostaglandin E (PGE2) in combination with selected siRNA(s) was proposed for the efficient treatment of idiopathic pulmonary fibrosis (IPF). Nanostructured lipid carriers (NLC) were used as a delivery system for PGE2 with and without siRNAs targeted to MMP3, CCL12, and HIF1Al...

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Udgivet i:Nanomedicine
Main Authors: Garbuzenko, O. B., Ivanova, V., Kholodovych, V., Reimer, D. C., Reuhl, K. R., Yurkow, E., Adler, D., Minko, T.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546883/
https://ncbi.nlm.nih.gov/pubmed/28434932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.04.005
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