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Upregulation of autophagy genes and the unfolded protein response in human heart failure

The cellular environment of the mammalian heart constantly is challenged with environmental and intrinsic pathological insults, which affect the proper folding of proteins in heart failure. The effects of damaged or misfolded proteins on the cell can be profound and result in a process termed “prote...

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Pubblicato in:Int J Clin Exp Med
Autori principali: Jensen, Brian C, Bultman, Scott J, Holley, Darcy, Tang, Wei, de Ridder, Gustaaf, Pizzo, Salvatore, Bowles, Dawn, Willis, Monte S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546743/
https://ncbi.nlm.nih.gov/pubmed/28794819
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