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Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer

Enhancer is critical cis regulatory elements in gene expression. To understand whether and how the aberrant enhancer activation may contribute to cancer risk, the differentially methylated enhancers (eDMRs) in normal and malignant breast tissues were identified and analyzed. By incorporating genome-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Yuan, Hao, Da-Peng, Li, Jing-Jing, Wang, Li, Di, Li-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546512/
https://ncbi.nlm.nih.gov/pubmed/28621677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18348
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