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Proteostasis control by the unfolded protein response
Stress induced by accumulation of misfolded proteins in the endoplasmic reticulum (ER) is observed in many physiological and pathological conditions. To cope with ER stress, cells activate the unfolded protein response (UPR), a dynamic signaling network that orchestrates the recovery of homeostasis...
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| Published in: | Nat Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546321/ https://ncbi.nlm.nih.gov/pubmed/26123108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3184 |
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