Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions

Human neutrophil elastase (HNE) is an important N-glycosylated serine protease in the innate immune system, but the structure and immune-modulating functions of HNE N-glycosylation remain undescribed. Herein, LC-MS/MS-based glycan, glycopeptide and glycoprotein profiling were utilized to first deter...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Loke, Ian, Østergaard, Ole, Heegaard, Niels H. H., Packer, Nicolle H., Thaysen-Andersen, Morten
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546201/
https://ncbi.nlm.nih.gov/pubmed/28630087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.066746
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker