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Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus

In this study, we described the generation and immunogenicity of the Zika Virus (ZIKV) envelope protein (E) domain III (DIII) as a protein subunit vaccine candidate. ZIKV EDIII (zEDIII) was rapidly produced in E. coli in inclusion bodies. ZIKV EDIII was solubilized, refolded and purified to >95%...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccine
Prif Awduron: Yang, Ming, Dent, Matthew, Lai, Huafang, Sun, Haiyan, Chen, Qiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546088/
https://ncbi.nlm.nih.gov/pubmed/28669618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.052
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