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Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus
In this study, we described the generation and immunogenicity of the Zika Virus (ZIKV) envelope protein (E) domain III (DIII) as a protein subunit vaccine candidate. ZIKV EDIII (zEDIII) was rapidly produced in E. coli in inclusion bodies. ZIKV EDIII was solubilized, refolded and purified to >95%...
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| Veröffentlicht in: | Vaccine |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546088/ https://ncbi.nlm.nih.gov/pubmed/28669618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.052 |
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