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Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus

In this study, we described the generation and immunogenicity of the Zika Virus (ZIKV) envelope protein (E) domain III (DIII) as a protein subunit vaccine candidate. ZIKV EDIII (zEDIII) was rapidly produced in E. coli in inclusion bodies. ZIKV EDIII was solubilized, refolded and purified to >95%...

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Bibliografske podrobnosti
izdano v:Vaccine
Main Authors: Yang, Ming, Dent, Matthew, Lai, Huafang, Sun, Haiyan, Chen, Qiang
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546088/
https://ncbi.nlm.nih.gov/pubmed/28669618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.052
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