Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus

In this study, we described the generation and immunogenicity of the Zika Virus (ZIKV) envelope protein (E) domain III (DIII) as a protein subunit vaccine candidate. ZIKV EDIII (zEDIII) was rapidly produced in E. coli in inclusion bodies. ZIKV EDIII was solubilized, refolded and purified to >95%...

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Enregistré dans:
Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Yang, Ming, Dent, Matthew, Lai, Huafang, Sun, Haiyan, Chen, Qiang
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546088/
https://ncbi.nlm.nih.gov/pubmed/28669618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.052
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