The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses

Inflammatory responses are elicited through lipid products of phospholipase A(2) activity that acts on the membrane phospholipids, including the phosphoinositides, to form the proinflammatory arachidonic acid and, in parallel, the glycerophosphoinositols. Here, we investigate the role of the glycero...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Vessichelli, Mariangela, Mariggiò, Stefania, Varone, Alessia, Zizza, Pasquale, Di Santo, Angelomaria, Amore, Concetta, Dell'Elba, Giuseppe, Cutignano, Adele, Fontana, Angelo, Cacciapuoti, Carmela, Di Costanzo, Gaetano, Zannini, Mariastella, de Cristofaro, Tiziana, Evangelista, Virgilio, Corda, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Lipids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546025/
https://ncbi.nlm.nih.gov/pubmed/28600357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773861
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