Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress

RATIONALE: Mitochondrial changes occur during cell differentiation and cardiovascular disease. Dynamin-related protein 1 (DRP1) is a key regulator of mitochondrial fission. We hypothesized that DRP1 plays a role in cardiovascular calcification, a process involving cell differentiation and a major cl...

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Veröffentlicht in:Circ Res
Hauptverfasser: Rogers, Maximillian A., Maldonado, Natalia, Hutcheson, Joshua D., Goettsch, Claudia, Goto, Shinji, Yamada, Iwao, Faits, Tyler, Sesaki, Hiromi, Aikawa, Masanori, Aikawa, Elena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546003/
https://ncbi.nlm.nih.gov/pubmed/28607103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.310293
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