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Disruption of microtubules in living cells and cell models by high affinity antibodies to beta-tubulin.

Polyclonal antibodies with high affinity for beta-tubulin were found to disrupt cytoplasmic microtubules efficiently after microinjection into tissue culture cells. The degree of microtubular fragmentation was directly proportional to the amount of the injected antibody. At molar ratios of 1 antibod...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Füchtbauer, A, Herrmann, M, Mandelkow, E M, Jockusch, B M
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1985
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3905386/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb04007.x
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