Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains

Recently, 125 loci with genome-wide support for association with schizophrenia were identified. We investigated the impact of these variants and their accumulated genetic risk on brain activation in five neurocognitive domains of the Research Domain Criteria (working memory, reward processing, episo...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Erk, S, Mohnke, S, Ripke, S, Lett, T A, Veer, I M, Wackerhagen, C, Grimm, O, Romanczuk-Seiferth, N, Degenhardt, F, Tost, H, Mattheisen, M, Mühleisen, T W, Charlet, K, Skarabis, N, Kiefer, F, Cichon, S, Witt, S H, Nöthen, M M, Rietschel, M, Heinz, A, Meyer-Lindenberg, A, Walter, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545733/
https://ncbi.nlm.nih.gov/pubmed/28072415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.272
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