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Alcohol-dose-dependent DNA methylation and expression in the nucleus accumbens identifies coordinated regulation of synaptic genes

Alterations in DNA methylation have been associated with alcohol exposure and proposed to contribute to continued alcohol use; however, the molecular mechanisms involved remain obscure. We investigated the escalating effects of alcohol use on DNA methylation, gene expression and predicted neural eff...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Cervera-Juanes, R, Wilhelm, L J, Park, B, Grant, K A, Ferguson, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545731/
https://ncbi.nlm.nih.gov/pubmed/28072409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.266
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