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Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain

The dopamine hypothesis of schizophrenia posits that increased subcortical dopamine underpins psychosis. In vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in schizophrenia; however, measures of the dopamine-syn...

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Bibliografische gegevens
Gepubliceerd in:Transl Psychiatry
Hoofdauteurs: Purves-Tyson, T D, Owens, S J, Rothmond, D A, Halliday, G M, Double, K L, Stevens, J, McCrossin, T, Shannon Weickert, C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545725/
https://ncbi.nlm.nih.gov/pubmed/28094812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.257
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