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Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain

The dopamine hypothesis of schizophrenia posits that increased subcortical dopamine underpins psychosis. In vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in schizophrenia; however, measures of the dopamine-syn...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Purves-Tyson, T D, Owens, S J, Rothmond, D A, Halliday, G M, Double, K L, Stevens, J, McCrossin, T, Shannon Weickert, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545725/
https://ncbi.nlm.nih.gov/pubmed/28094812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.257
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