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Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain

The dopamine hypothesis of schizophrenia posits that increased subcortical dopamine underpins psychosis. In vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in schizophrenia; however, measures of the dopamine-syn...

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書目詳細資料
發表在:Transl Psychiatry
Main Authors: Purves-Tyson, T D, Owens, S J, Rothmond, D A, Halliday, G M, Double, K L, Stevens, J, McCrossin, T, Shannon Weickert, C
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545725/
https://ncbi.nlm.nih.gov/pubmed/28094812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.257
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