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Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration

Brain autopsy and biomarker studies indicate that the pathology of Alzheimer’s disease (AD) is initiated at least 10–20 years before clinical symptoms. This provides a window of opportunity to initiate preventive treatment. However, this emphasizes the necessity for biomarkers that identify individu...

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Bibliographic Details
Published in:Transl Psychiatry
Main Authors: Höglund, K, Kern, S, Zettergren, A, Börjesson-Hansson, A, Zetterberg, H, Skoog, I, Blennow, K
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545720/
https://ncbi.nlm.nih.gov/pubmed/28072416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.252
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