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A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology
It has been proposed that vulnerability to nicotine addiction is moderated by variation at the μ-opioid receptor locus (OPRM1), but results from human studies vary and prospective studies based on genotype are lacking. We have developed a humanized mouse model of the most common functional OPRM1 pol...
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| Publicado no: | Transl Psychiatry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5545715/ https://ncbi.nlm.nih.gov/pubmed/27459726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.132 |
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