Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration

The cell adhesion molecule neuroplastin (Np) is a novel candidate to influence human intelligence. Np-deficient mice display complex cognitive deficits and reduced levels of Plasma Membrane Ca(2+) ATPases (PMCAs), an essential regulator of the intracellular Ca(2+) concentration ([iCa(2+)]) and neuro...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Herrera-Molina, Rodrigo, Mlinac-Jerkovic, Kristina, Ilic, Katarina, Stöber, Franziska, Vemula, Sampath Kumar, Sandoval, Mauricio, Milosevic, Natasa Jovanov, Simic, Goran, Smalla, Karl-Heinz, Goldschmidt, Jürgen, Bognar, Svjetlana Kalanj, Montag, Dirk
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544750/
https://ncbi.nlm.nih.gov/pubmed/28779130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07839-9
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