MTHFR gene variants and non-MALT lymphoma development in primary Sjogren’s syndrome

Primary Sjogren’s syndrome (pSS) confers increased risk for non-Hodgkin lymphoma (NHL) development. Two common polymorphisms, the c. 677C > T and c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an enzyme essential in DNA synthesis and methylation, have been associated w...

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Pubblicato in:Sci Rep
Autori principali: Fragkioudaki, Sofia, Nezos, Adrianos, Souliotis, Vassilis L., Chatziandreou, Ilenia, Saetta, Angelica A., Drakoulis, Nikolaos, Tzioufas, Athanasios G., Voulgarelis, Michael, Sfikakis, Petros P., Koutsilieris, Michael, Crow, Mary K., Moutsopoulos, Haralampos M., Mavragani, Clio P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544668/
https://ncbi.nlm.nih.gov/pubmed/28779180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07347-w
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