Rescue of Deficient Amygdala Tonic γ-Aminobutyric Acidergic Currents in the Fmr(−/y) Mouse Model of Fragile X Syndrome by a Novel γ-Aminobutyric Acid Type A Receptor-Positive Allosteric Modulator

Alterations in the ratio of excitatory to inhibitory transmission are emerging as a common component of many nervous system disorders, including autism spectrum disorders (ASDs). Tonic γ-aminobutyric acidergic (GABAergic) transmission provided by peri- and extrasynaptic GABA type A (GABA(A)) recepto...

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Publicado en:J Neurosci Res
Autores principales: Martin, Brandon S., Martinez-Botella, Gabriel, Loya, Carlos M., Salituro, Francesco G., Robichaud, Albert J., Huntsman, Molly M., Ackley, Mike A., Doherty, James J., Corbin, Joshua G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544527/
https://ncbi.nlm.nih.gov/pubmed/26308557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23632
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