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The two intervening sequences of human beta- and gamma-globin pre-mRNAs are excised in a preferred temporal order in vitro.

Splicing of complete synthetic human beta- and gamma-globin mRNA precursors (pre-mRNAs) follows a preferred pathway in vitro. In almost all molecules, excision of the first intervening sequence (IVS) is completed before excision of the second IVS initiates. However, in a very small fraction of molec...

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Detalhes bibliográficos
Main Authors: Lang, K M, van Santen, V L, Spritz, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554452/
https://ncbi.nlm.nih.gov/pubmed/3851741
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