Randomized Controlled Trial of Mineralocorticoid Receptor Blockade in Children with Chronic Kidney Allograft Nephropathy

BACKGROUND AND OBJECTIVES: We showed that mineralocorticoid receptor blockade (MRB) prevented acute and chronic cyclosporine nephropathy (CsA-Nx) in the rat. The aim of this translational study was to investigate the effect of long-term eplerenone administration on renal allograft function in childr...

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Publicado en:Clin J Am Soc Nephrol
Autores principales: Medeiros, Mara, Velásquez-Jones, Luis, Hernández, Ana M., Ramón-García, Guillermo, Valverde, Saúl, Fuentes, Yolanda, Vargas, Arindal, Patiño, Mauricio, Pérez-Villalva, Rosalba, Ortega-Trejo, Juan Antonio, Barrera-Chimal, Jonatan, Bobadilla, Norma A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544507/
https://ncbi.nlm.nih.gov/pubmed/28536123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05300516
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