Mild ischemic Injury Leads to Long-Term Alterations in the Kidney: Amelioration by Spironolactone Administration

Administration of the mineralocorticoid receptor antagonist spironolactone prevents the development of chronic kidney disease (CKD) after a severe ischemic injury. However, whether brief periods of ischemia lead to CKD and whether spironolactone administration after ischemia may be a useful therapeu...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Barrera-Chimal, Jonatan, Pérez-Villalva, Rosalba, Ortega, Juan Antonio, Sánchez, Andrea, Rodríguez-Romo, Roxana, Durand, Marta, Jaisser, Frederic, Bobadilla, Norma A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495407/
https://ncbi.nlm.nih.gov/pubmed/26157344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.11729
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