Maturation of selected human mitochondrial tRNAs requires deadenylation

Human mitochondria contain a genome (mtDNA) that encodes essential subunits of the oxidative phosphorylation system. Expression of mtDNA entails multi-step maturation of precursor RNA. In other systems, the RNA life cycle involves surveillance mechanisms, however, the details of RNA quality control...

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Udgivet i:eLife
Main Authors: Pearce, Sarah F, Rorbach, Joanna, Haute, Lindsey Van, D’Souza, Aaron R, Rebelo-Guiomar, Pedro, Powell, Christopher A, Brierley, Ian, Firth, Andrew E, Minczuk, Michal
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Genes and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544427/
https://ncbi.nlm.nih.gov/pubmed/28745585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27596
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