Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature

Cytochrome c oxidase (CcO), the terminal enzyme in the electron transfer chain, translocates protons across the inner mitochondrial membrane by harnessing the free energy generated by the reduction of oxygen to water. Several redox-coupled proton translocation mechanisms have been proposed, but they...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ishigami, Izumi, Zatsepin, Nadia A., Hikita, Masahide, Conrad, Chelsie E., Nelson, Garrett, Coe, Jesse D., Basu, Shibom, Grant, Thomas D., Seaberg, Matthew H., Sierra, Raymond G., Hunter, Mark S., Fromme, Petra, Fromme, Raimund, Yeh, Syun-Ru, Rousseau, Denis L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544322/
https://ncbi.nlm.nih.gov/pubmed/28698372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705628114
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