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Functional characterization of human pluripotent stem cell-derived arterial endothelial cells

Here, we report the derivation of arterial endothelial cells from human pluripotent stem cells that exhibit arterial-specific functions in vitro and in vivo. We combine single-cell RNA sequencing of embryonic mouse endothelial cells with an EFNB2-tdTomato/EPHB4-EGFP dual reporter human embryonic ste...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Jue, Chu, Li-Fang, Hou, Zhonggang, Schwartz, Michael P., Hacker, Timothy, Vickerman, Vernella, Swanson, Scott, Leng, Ning, Nguyen, Bao Kim, Elwell, Angela, Bolin, Jennifer, Brown, Matthew E., Stewart, Ron, Burlingham, William J., Murphy, William L., Thomson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544294/
https://ncbi.nlm.nih.gov/pubmed/28696312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702295114
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