Functional characterization of human pluripotent stem cell-derived arterial endothelial cells

Here, we report the derivation of arterial endothelial cells from human pluripotent stem cells that exhibit arterial-specific functions in vitro and in vivo. We combine single-cell RNA sequencing of embryonic mouse endothelial cells with an EFNB2-tdTomato/EPHB4-EGFP dual reporter human embryonic ste...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zhang, Jue, Chu, Li-Fang, Hou, Zhonggang, Schwartz, Michael P., Hacker, Timothy, Vickerman, Vernella, Swanson, Scott, Leng, Ning, Nguyen, Bao Kim, Elwell, Angela, Bolin, Jennifer, Brown, Matthew E., Stewart, Ron, Burlingham, William J., Murphy, William L., Thomson, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544294/
https://ncbi.nlm.nih.gov/pubmed/28696312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702295114
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