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Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells

Global transcriptomic and proteomic analyses of T cells have been rich sources of unbiased data for understanding T-cell activation. Lack of full concordance of these datasets has illustrated that important facets of T-cell activation are controlled at the level of translation. We undertook translat...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Tan, Thomas C. J., Knight, John, Sbarrato, Thomas, Dudek, Kate, Willis, Anne E., Zamoyska, Rose
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544288/
https://ncbi.nlm.nih.gov/pubmed/28696283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700939114
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