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Filament-like DREP4 CIDE domain: characterization and preliminary X-ray crystallographic studies

DREP4 is a nuclease from fruit fly that is involved in apoptotic DNA fragmentation. DREP4 contains a conserved CIDE domain that acts as a protein-interaction module and is critical for its function. In this study, it was found that DREP4 CIDE domains form filament-like structures in solution. The le...

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Библиографические подробности
Опубликовано в: :Acta Crystallogr F Struct Biol Commun
Главный автор: Park, Hyun Ho
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544006/
https://ncbi.nlm.nih.gov/pubmed/28777092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1701069X
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