Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro

Transcript profiling of 27 normal colon mucosas and 258 adenocarcinomas showed Keratin23 to be increased in 78% microsatellite‐stable tumors, while microsatellite‐instable tumors showed low transcript levels, comparable to normal mucosas. Immunohistochemical analyses demonstrated that 88% of microsa...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Birkenkamp-Demtroder, Karin, Mansilla, Francisco, Sørensen, Flemming Brandt, Kruhøffer, Mogens, Cabezón, Teresa, Christensen, Lise Lotte, Aaltonen, Lauri A., Verspaget, Hein W., Falck Ørntoft, Torben
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2007
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543893/
https://ncbi.nlm.nih.gov/pubmed/19383294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.05.005
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